Shanghai Science and Technology Museum is located at No. 2000 of the Century Avenue (Shiji Dadao). It promotes science, education, cultural and ideological progress. It aims at offering visitors a unique experience in the modern scientific discipline under the theme of 'Nature, People and Science'.

The museum is composed of a basement and four floors above ground. It rises in a spiral, symbolizing scientific progress. A huge glass sphere embedded in a pool of clear water, at the building's midpoint, gives the theme of life renewed. The first floor houses the Hall of Widest Spectrum of Life which captures the scenery in Yunnan Province. The Earth's Crust Exploration Hall reveals the secrets of the earth and Shanghai's physical geography. The Light of Wisdom Hall demonstrates chemistry, biology and maths with a large number of interactive items. The Children's Techno-Land is designed for children between one and twelve years old, to interest them early in scientific matters. Besides, the Cradle of Designers and the IWERKS 4-D Theatre are also worth visiting.

The second floor includes the Hall of Earth Home, the Hall of Information Age, the Seeker Corridor, the Robot World and the Spider Exhibition Hall, all of which are full of wonder and excitement. The third floor is the place of the Hall of Exploration Light, the Astronavigation World, the Hall of People and Health, and the Space Theatre. The fourth floor is the conference hall.